PrimePCR™ ddPCR™ Expression EvaGreen® Assay: WWOX, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038777; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006683
Chromosome Location:   16:78133585-78133770question
Amplicon Length:   156

Gene Information

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation transcription and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis ovary and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis suggesting a similar important role in apoptosis for the human protein. In addition there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   WWOX
Gene Name:   WW domain containing oxidoreductase
Aliases:   D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SDR41C1, WOX1
RefSeq:   NC_000016.9 NG_011698.1 NT_010498.15
Ensembl:   ENSG00000186153
Entrez:   51741
UniGene:   Hs.461453
Chromosome Mapping:   16q23.3-q24.1

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