PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PILRA, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038618; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006613
Chromosome Location:   7:99997488-99997649question
Amplicon Length:   132

Gene Information

Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants each encoding a distinct isoform are described. [provided by RefSeq Jul 2008]

Gene Symbol:   PILRA
Gene Name:   paired immunoglobin-like type 2 receptor alpha
Aliases:   FDF03
RefSeq:   NC_000007.13 NT_007933.15
Ensembl:   ENSG00000085514
Entrez:   29992
UniGene:   Hs.444407
Chromosome Mapping:   7q22.1

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