PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SERPINB10, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038564; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006582
Chromosome Location:   18:61582747-61582899question
Amplicon Length:   123

Gene Information

The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation fibrinolysis coagulation cellular differentiation tumor suppression apoptosis and cell migration. Serpins are characterized by a well-conserved tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell 1989 [PubMed 2690952]). A critical portion of the molecule the reactive center loop connects beta sheets A and C. Protease inhibitor-10 (PI10; SERPINB10) is a member of the ov-serpin subfamily which relative to the archetypal serpin PI1 (MIM 107400) is characterized by a high degree of homology to chicken ovalbumin lack of N- and C-terminal extensions absence of a signal peptide and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al. 1997 [PubMed 9268635]).[supplied by OMIM Jan 2010]

Gene Symbol:   SERPINB10
Gene Name:   serpin peptidase inhibitor, clade B (ovalbumin), member 10
Aliases:   PI10, bomapin
RefSeq:   NC_000018.9 NT_025028.14
Ensembl:   ENSG00000242550
Entrez:   5273
UniGene:   Hs.158339
Chromosome Mapping:   18q21.3

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