PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MECP2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038147; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006422
Chromosome Location:   X:153297894-153363075question
Amplicon Length:   99

Gene Information

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2 MBD1 MBD2 MBD3 and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins with the exception of MBD3 is capable of binding specifically to methylated DNA. MECP2 MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq Jul 2009]

Gene Symbol:   MECP2
Gene Name:   methyl CpG binding protein 2 (Rett syndrome)
Aliases:   AUTSX3, DKFZp686A24160, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT
RefSeq:   NC_000023.10 NT_167198.1 NG_007107.1 NG_008387.1
Ensembl:   ENSG00000169057
Entrez:   4204
UniGene:   Hs.731393
Chromosome Mapping:   Xq28

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