PrimePCR™ ddPCR™ Expression EvaGreen® Assay: VKORC1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038134; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006415
Chromosome Location:   16:31102520-31102643question
Amplicon Length:   94

Gene Information

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 23-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin and it is the product of this gene that is sensitive to warfarin. In humans mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and in humans and rats with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   VKORC1
Gene Name:   vitamin K epoxide reductase complex, subunit 1
Aliases:   EDTP308, FLJ00289, IMAGE3455200, MGC2694, MST134, MST576, VKCFD2, VKOR
RefSeq:   NC_000016.9 NG_011564.1 NT_010393.16
Ensembl:   ENSG00000167397
Entrez:   79001
UniGene:   Hs.324844
Chromosome Mapping:   16p11.2

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