PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DCLK1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0038039; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006376
Chromosome Location:   13:36428636-36445371question
Amplicon Length:   75

Gene Information

This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains which bind microtubules and regulate microtubule polymerization a C-terminal serine/threonine protein kinase domain which shows substantial homology to Ca2+/calmodulin-dependent protein kinase and a serine/proline-rich domain in between the doublecortin and the protein kinase domains which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes including neuronal migration retrograde transport neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms which are differentially expressed and have different kinase activities.[provided by RefSeq Sep 2010]

Gene Symbol:   DCLK1
Gene Name:   doublecortin-like kinase 1
Aliases:   CL1, CLICK1, DCAMKL1, DCDC3A, DCLK, KIAA0369
RefSeq:   NC_000013.10 NT_024524.14
Ensembl:   ENSG00000133083
Entrez:   9201
UniGene:   Hs.507755
Chromosome Mapping:   13q13

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