PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SMAD1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0037732; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006217
Chromosome Location:   4:146435635-146435790question
Amplicon Length:   126

Gene Information

The protein encoded by this gene belongs to the SMAD a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs) which are involved in a range of biological activities including cell growth apoptosis morphogenesis development and immune responses. In response to BMP ligands this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4 which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases such as SMURF1 and SMURF2 and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq Jul 2008]

Gene Symbol:   SMAD1
Gene Name:   SMAD family member 1
Aliases:   BSP1, JV4-1, JV41, MADH1, MADR1
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000170365
Entrez:   4086
UniGene:   Hs.604588
Chromosome Mapping:   4q31

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