PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CTSC, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0037620; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006146
Chromosome Location:   11:88068105-88068208question
Amplicon Length:   74

Gene Information

The protein encoded by this gene a member of the peptidase C1 family is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains both produced from a single protein precursor and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CTSC
Gene Name:   cathepsin C
Aliases:   CPPI, DPP1, DPPI, HMS, JP, JPD, PALS, PLS
RefSeq:   NC_000011.9 NT_167190.1 NG_007952.1
Ensembl:   ENSG00000109861
Entrez:   1075
UniGene:   Hs.128065
Chromosome Mapping:   11q14.2

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