This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCED0037589; exonic
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23 a protein involved in nucleotide excision repair (NER). This protein was shown to interact with and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG) which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain which was reported to interact with 26S proteasome as well as with ubiquitin protein ligase E6AP and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. [provided by RefSeq Jul 2008]