PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PPARD, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0037583; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006113
Chromosome Location:   6:35392254-35392359question
Amplicon Length:   76

Gene Information

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes and may be involved in the development of several chronic diseases including diabetes obesity atherosclerosis and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC) a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum lipid metabolism and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq Jan 2010]

Gene Symbol:   PPARD
Gene Name:   peroxisome proliferator-activated receptor delta
Aliases:   FAAR, MGC3931, NR1C2, NUC1, NUCI, NUCII, PPARB
RefSeq:   NC_000006.11 NT_007592.15 NG_012345.1
Ensembl:   ENSG00000112033
Entrez:   5467
UniGene:   Hs.696032
Chromosome Mapping:   6p21.2

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