PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GPX1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0037003; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006048
Chromosome Location:   3:49394616-49394747question
Amplicon Length:   102

Gene Information

This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine which occurs at the active site of glutathione peroxidase and is coded by UGA that normally functions as a translation termination codon. In addition this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region which includes three alleles with five six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   GPX1
Gene Name:   glutathione peroxidase 1
Aliases:   GSHPX1, MGC14399, MGC88245
RefSeq:   NC_000003.11 NG_012264.1 NT_022517.18
Ensembl:   ENSG00000233276
Entrez:   2876
UniGene:   Hs.76686
Chromosome Mapping:   3p21.3

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