PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SIRPA, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036953; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006016
Chromosome Location:   20:1918915-1919027question
Amplicon Length:   83

Gene Information

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP) and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   SIRPA
Gene Name:   signal-regulatory protein alpha
Aliases:   BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP
RefSeq:   NC_000020.10 NT_011387.8
Ensembl:   ENSG00000198053
Entrez:   140885
UniGene:   Hs.581021
Chromosome Mapping:   20p13

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