PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PRF1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036864; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005960
Chromosome Location:   10:72357466-72357598question
Amplicon Length:   103

Gene Information

The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9 this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2) a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq Jul 2008]

Gene Symbol:   PRF1
Gene Name:   perforin 1 (pore forming protein)
Aliases:   FLH2, HPLH2, MGC65093, P1, PFN1, PFP
RefSeq:   NC_000010.10 NG_009615.1 NT_030059.13
Ensembl:   ENSG00000180644
Entrez:   5551
UniGene:   Hs.2200
Chromosome Mapping:   10q22

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