PrimePCR™ ddPCR™ Expression EvaGreen® Assay: BCL2L1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036793; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005911
Chromosome Location:   20:30309967-30310109question
Amplicon Length:   113

Gene Information

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants which encode distinct isoforms have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq Jul 2008]

Gene Symbol:   BCL2L1
Gene Name:   BCL2-like 1
Aliases:   BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, DKFZp781P2092, bcl-xL, bcl-xS
RefSeq:   NC_000020.10 NT_011362.10
Ensembl:   ENSG00000171552
Entrez:   598
UniGene:   Hs.516966
Chromosome Mapping:   20q11.21

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