PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DUSP6, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036582; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005780
Chromosome Location:   12:89743092-89743203question
Amplicon Length:   82

Gene Information

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK SAPK/JNK p38) which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases different tissue distribution and subcellular localization and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2 is expressed in a variety of tissues with the highest levels in heart and pancreas and unlike most other members of this family is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   DUSP6
Gene Name:   dual specificity phosphatase 6
Aliases:   MKP3, PYST1
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000139318
Entrez:   1848
UniGene:   Hs.298654
Chromosome Mapping:   12q22-q23

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