PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ABI1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036565; exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005773
Chromosome Location:   10:27037473-27037590question
Amplicon Length:   88

Gene Information

This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma colon cancer and breast cancer and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq Sep 2011]

Gene Symbol:   ABI1
Gene Name:   abl-interactor 1
Aliases:   ABI-1, E3B1, NAP1BP, SSH3BP, SSH3BP1
RefSeq:   NC_000010.10 NG_008972.1 NT_008705.16
Ensembl:   ENSG00000136754
Entrez:   10006
UniGene:   Hs.508148
Chromosome Mapping:   10p11.2

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