PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ZP4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036446; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005697
Chromosome Location:   1:238053910-238054049question
Amplicon Length:   110

Gene Information

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence a conserved ZP domain a consensus furin cleavage site and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. [provided by RefSeq Jul 2008]

Gene Symbol:   ZP4
Gene Name:   zona pellucida glycoprotein 4
Aliases:   ZBP, ZP1, ZPB, Zp-4
RefSeq:   NC_000001.10 NT_167186.1
Ensembl:   ENSG00000116996
Entrez:   57829
UniGene:   Hs.136241
Chromosome Mapping:   1q43

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