PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GNRHR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036409; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005679
Chromosome Location:   4:68619691-68619814question
Amplicon Length:   94

Gene Information

This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes breast ovary and prostate. Following binding of gonadotropin-releasing hormone the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   GNRHR
Gene Name:   gonadotropin-releasing hormone receptor
RefSeq:   NC_000004.11 NG_009293.1 NT_022778.16
Ensembl:   ENSG00000109163
Entrez:   2798
UniGene:   Hs.407587
Chromosome Mapping:   4q21.2

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