PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MID1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036377; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005659
Chromosome Location:   X:10535504-10535602question
Amplicon Length:   69

Gene Information

The protein encoded by this gene is a member of the tripartite motif (TRIM) family also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains a RING a B-box type 1 and a B-box type 2 and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome which is characterized by midline abnormalities such as cleft lip laryngeal cleft heart defects hypospadias and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing; however the full-length nature of some of the variants has not been determined. [provided by RefSeq Jul 2010]

Gene Symbol:   MID1
Gene Name:   midline 1 (Opitz/BBB syndrome)
Aliases:   BBBG1, FLJ57031, FLJ58683, FLJ76288, FXY, GBBB1, MIDIN, OGS1, OS, OSX, RNF59, TRIM18, XPRF, ZNFXY
RefSeq:   NC_000023.10 NT_167197.1 NG_008197.1
Ensembl:   ENSG00000101871
Entrez:   4281
UniGene:   Hs.27695
Chromosome Mapping:   Xp22

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