PrimePCR™ ddPCR™ Expression EvaGreen® Assay: PATZ1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036362; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005649
Chromosome Location:   22:31741134-31741268question
Amplicon Length:   105

Gene Information

The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor it is postulated to be a repressor of gene expression. In small round cell sarcoma this gene is fused to EWS by a small inversion of 22q then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   PATZ1
Gene Name:   POZ (BTB) and AT hook containing zinc finger 1
Aliases:   MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG, dJ400N23
RefSeq:   NC_000022.10 NT_011520.12
Ensembl:   ENSG00000100105
Entrez:   23598
UniGene:   Hs.731398
Chromosome Mapping:   22q12.2

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