PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ALX4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0036312; exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005625
Chromosome Location:   11:44284287-44284435question
Amplicon Length:   119

Gene Information

This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones limbs hair teeth and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development mesenchymal-epithelial communication and hair follicle development. Deletion of a segment of chromosome 11 containing this gene del(11)(p11p12) causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies mental retardation multiple exostoses and genital abnormalities in males. In mouse this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq Oct 2009]

Gene Symbol:   ALX4
Gene Name:   ALX homeobox 4
Aliases:   FND2, KIAA1788
RefSeq:   NC_000011.9 NG_015809.1 NT_009237.18
Ensembl:   ENSG00000052850
Entrez:   60529
UniGene:   Hs.436055
Chromosome Mapping:   11p11.2

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