PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DUSP4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0034774; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005524
Chromosome Location:   8:29195799-29195912question
Amplicon Length:   84

Gene Information

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK SAPK/JNK p38) which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases different tissue distribution and subcellular localization and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 ERK2 and JNK is expressed in a variety of tissues and is localized in the nucleus. Two alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. In addition multiple polyadenylation sites have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   DUSP4
Gene Name:   dual specificity phosphatase 4
Aliases:   HVH2, MKP-2, MKP2, TYP
RefSeq:   NC_000008.10 NT_167187.1
Ensembl:   ENSG00000120875
Entrez:   1846
UniGene:   Hs.417962
Chromosome Mapping:   8p12-p11

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