PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ASPH, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0034373; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005389
Chromosome Location:   8:62596611-62596709question
Amplicon Length:   69

Gene Information

This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins including protein C coagulation factors VII IX and X and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin triadin and the ryanodine receptor and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis. [provided by RefSeq Sep 2009]

Gene Symbol:   ASPH
Gene Name:   aspartate beta-hydroxylase
Aliases:   AAH, BAH, CASQ2BP1, HAAH, JCTN, junctin
RefSeq:   NC_000008.10 NT_008183.19 NG_013210.1
Ensembl:   ENSG00000198363
Entrez:   444
UniGene:   Hs.332422
Chromosome Mapping:   8q12.1

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