PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SIGLEC8, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0033940; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005175
Chromosome Location:   19:51961216-51961306question
Amplicon Length:   61

Gene Information

Sialic acid-binding immunoglobulin (Ig)-like lectins or SIGLECs (e.g. CD33 (MIM 159590)) are a family of type 1 transmembrane proteins each having a unique expression pattern mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif or ITIM (see MIM 604964) and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al. 2000 [PubMed 11095983]).[supplied by OMIM May 2010]

Gene Symbol:   SIGLEC8
Gene Name:   sialic acid binding Ig-like lectin 8
Aliases:   MGC59785, SAF2, SIGLEC-8, SIGLEC8L
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000105366
Entrez:   27181
UniGene:   Hs.447899
Chromosome Mapping:   19q13.33-q13.41

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