PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TCL1A, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0033928; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5005167
Chromosome Location:   14:96178601-96180308question
Amplicon Length:   127

Gene Information

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al. 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al. 2000 [PubMed 10983986]).[supplied by OMIM Jul 2010]

Gene Symbol:   TCL1A
Gene Name:   T-cell leukemia/lymphoma 1A
Aliases:   TCL1
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000100721
Entrez:   8115
UniGene:   Hs.2484
Chromosome Mapping:   14q32.1

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