PrimePCR™ ddPCR™ Expression EvaGreen® Assay: KCNA1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0021102; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5004889
Chromosome Location:   12:5021889-5022037question
Amplicon Length:   119

Gene Information

This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6) and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq Jul 2008]

Gene Symbol:   KCNA1
Gene Name:   potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
Aliases:   AEMK, EA1, HBK1, HUK1, KV1.1, MBK1, MGC126782, MGC138385, MK1, RBK1
RefSeq:   NC_000012.11 NG_011815.1 NT_009759.16
Ensembl:   ENSG00000111262
Entrez:   3736
UniGene:   Hs.416139
Chromosome Mapping:   12p13.32

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