PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GCSH, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0020644; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5004805
Chromosome Location:   16:81115677-81115836question
Amplicon Length:   130

Gene Information

Degradation of glycine is brought about by the glycine cleavage system which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase) H protein (a lipoic acid-containing protein) T protein (a tetrahydrofolate-requiring enzyme) and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants one protein-coding and the other probably not protein-codinghave been found for this gene. Also several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq Jan 2010]

Gene Symbol:   GCSH
Gene Name:   glycine cleavage system protein H (aminomethyl carrier)
Aliases:   GCE, NKH
RefSeq:   NC_000016.9 NG_016427.1 NT_010498.15
Ensembl:   ENSG00000140905
Entrez:   2653
UniGene:   Hs.546256
Chromosome Mapping:   16q23.2

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