PrimePCR™ ddPCR™ Expression EvaGreen® Assay: E2F6, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0020448; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5004762
Chromosome Location:   2:11585342-11585444question
Amplicon Length:   73

Gene Information

This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP) a transactivation domain enriched in acidic amino acids and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene but it has not been clearly demonstrated that they encode valid isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   E2F6
Gene Name:   E2F transcription factor 6
Aliases:   E2F-6, MGC111545
RefSeq:   NC_000002.11 NT_005334.16
Ensembl:   ENSG00000169016
Entrez:   1876
UniGene:   Hs.603093
Chromosome Mapping:   2p25.1

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