PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GP5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0019916; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5004630
Chromosome Location:   3:194118464-194118570question
Amplicon Length:   77

Gene Information

Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720) that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA GP1BB and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200) a bleeding disorder (review by Lopez et al. 1998 [PubMed 9616133]).[supplied by OMIM Nov 2010]

Gene Symbol:   GP5
Gene Name:   glycoprotein V (platelet)
Aliases:   CD42d
RefSeq:   NC_000003.11 NT_029928.13
Ensembl:   ENSG00000178732
Entrez:   2814
UniGene:   Hs.73734
Chromosome Mapping:   3q29

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