PrimePCR™ ddPCR™ Expression EvaGreen® Assay: FADD, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0019883; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5004617
Chromosome Location:   11:70052327-70052438question
Amplicon Length:   82

Gene Information

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain this protein can be recruited by TNFRSF6/Fas-receptor tumor necrosis factor receptor TNFRSF25 and TNFSF10/TRAIL-receptor and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein which allows it to recruit caspase-8 and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq Jul 2008]

Gene Symbol:   FADD
Gene Name:   Fas (TNFRSF6)-associated via death domain
Aliases:   MGC8528, MORT1
RefSeq:   NC_000011.9 NG_027966.1 NT_167190.1
Ensembl:   ENSG00000168040
Entrez:   8772
UniGene:   Hs.86131
Chromosome Mapping:   11q13.3

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