This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCED0019627; Exonic
This gene product constitutes one of the subunits of the multisubunit particle called exosome which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known however it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs) but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs thereby promoting their rapid degradation. [provided by RefSeq Jul 2008]