PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ERVW-1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0019407; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5004355
Chromosome Location:   7:92098208-92098358question
Amplicon Length:   121

Gene Information

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq Mar 2010]

Gene Symbol:   ERVW-1
Gene Name:   endogenous retrovirus group W, member 1
Aliases:   ENV, ENVW, ERVWE1, HERV-7q, HERV-W-ENV, HERV7Q, HERVW, HERVWENV
RefSeq:   NC_000007.13 NG_004112.1 NT_007933.15
Ensembl:   ENSG00000242950
Entrez:   30816
UniGene:   Not Available
Chromosome Mapping:   7q21.2

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