PrimePCR™ ddPCR™ Expression EvaGreen® Assay: GALR2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0003700; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5002101
Chromosome Location:   17:74071032-74071169question
Amplicon Length:   108

Gene Information

Galanin is an important neuromodulator present in the brain gastrointestinal system and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion inhibits cardiac vagal slowing of heart rate abolishes sinus arrhythmia and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq) in contrast to GALR1 which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq Jul 2008]

Gene Symbol:   GALR2
Gene Name:   galanin receptor 2
Aliases:   GALNR2, MGC125983, MGC125984
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000182687
Entrez:   8811
UniGene:   Hs.666366
Chromosome Mapping:   17q25.3

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