This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCED0003623; Exonic
The protein encoded by this gene is an endocytic receptor involved in several cellular processes including intracellular signaling lipid homeostasis and clearance of apoptotic cells. In addition the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq Jan 2010]