This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.
Info: EG; Same primer pair as used in qPCR assay qHsaCED0003576; Exonic
The protein encoded by this gene is a transcriptional activator of several genes including insulin somatostatin glucokinase islet amyloid polypeptide and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM) as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq Jul 2008]