PrimePCR™ ddPCR™ Expression EvaGreen® Assay: NDUFV1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0003526; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5001964
Chromosome Location:   11:67376923-67377032question
Amplicon Length:   80

Gene Information

The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10000 live births. Mitochondrial complex I deficiency is linked to myopathies encephalomyopathies and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq Oct 2009]

Gene Symbol:   NDUFV1
Gene Name:   NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
Aliases:   CI-51K, CI51KD, FLJ59059, UQOR1
RefSeq:   NC_000011.9 NT_167190.1 NG_013353.1
Ensembl:   ENSG00000167792
Entrez:   4723
UniGene:   Hs.7744
Chromosome Mapping:   11q13

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