PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CMA1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0003486; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5001933
Chromosome Location:   14:24975675-24975791question
Amplicon Length:   87

Gene Information

This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix the regulation of submucosal gland secretion and the generation of vasoactive peptides. In the heart and blood vessels this protein rather than angiotensin converting enzyme is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension cardiac hypertrophy and heart failure. Thus this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq Jul 2008]

Gene Symbol:   CMA1
Gene Name:   chymase 1, mast cell
Aliases:   CYH, MCT1, MGC119890, MGC119891, chymase
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000092009
Entrez:   1215
UniGene:   Hs.135626
Chromosome Mapping:   14q11.2

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