PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CASP12, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0003450; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5001909
Chromosome Location:   11:104768053-104768176question
Amplicon Length:   94

Gene Information

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq Feb 2011]

Gene Symbol:   CASP12
Gene Name:   caspase 12 (gene/pseudogene)
Aliases:   CASP-12, CASP12P1
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000204403
Entrez:   100506742
UniGene:   Hs.476989
Chromosome Mapping:   11q22.3

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10033487 ddPCR™ Mutation Detection Assays Product Insert, Ver C Click to download
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10041702 PrimePCR™ ddPCR™ Gene Expression Assays (EvaGreen) Product Insert, Rev A Click to download
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