PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CHMP4B, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0003188; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5001709
Chromosome Location:   20:32441849-32441998question
Amplicon Length:   120

Gene Information

This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III) which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP also known as ALIX) which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq Oct 2009]

Gene Symbol:   CHMP4B
Gene Name:   chromatin modifying protein 4B
Aliases:   C20orf178, CHMP4A, CTPP3, SNF7, SNF7-2, Shax1, VPS32B, Vps32-2, dJ553F4.4
RefSeq:   NC_000020.10 NG_015820.1 NT_011362.10
Ensembl:   ENSG00000101421
Entrez:   128866
UniGene:   Hs.472471
Chromosome Mapping:   20q11.22

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