PrimePCR™ ddPCR™ Expression EvaGreen® Assay: DIO2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0003068; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5001621
Chromosome Location:   14:80669493-80669596question
Amplicon Length:   74

Gene Information

The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 33'5-triiodothyronine (T3). It is highly expressed in the thyroid and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure the sec insertion sequence (SECIS) which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   DIO2
Gene Name:   deiodinase, iodothyronine, type II
Aliases:   5DII, D2, SelY, TXDI2
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000211448
Entrez:   1734
UniGene:   Hs.202354
Chromosome Mapping:   14q24.2-q24.3

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