PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CRYBB2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002761; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5001402
Chromosome Location:   22:25620909-25623839question
Amplicon Length:   84

Gene Information

Crystallins are separated into two classes: taxon-specific or enzyme and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development these crystallins are made and then retained throughout life making them extremely stable proteins. Mammalian lens crystallins are divided into alpha beta and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs a connecting peptide and N- and C-terminal extensions. Beta-crystallins the most heterogeneous differ by the presence of the C-terminal extension (present in the basic group none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene a beta basic group member is part of a gene cluster with beta-A4 beta-B1 and beta-B3. A chain-terminating mutation was found to cause type 2 cerulean cataracts. [provided by RefSeq Jul 2008]

Gene Symbol:   CRYBB2
Gene Name:   crystallin, beta B2
Aliases:   CCA2, CRYB2, CRYB2A, D22S665
RefSeq:   NC_000022.10 NG_009827.1 NT_011520.12
Ensembl:   ENSG00000244752
Entrez:   1415
UniGene:   Hs.373074
Chromosome Mapping:   22q11.2-q12.1,22q11.23

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