PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CRYGS, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002655; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5001316
Chromosome Location:   3:186256530-186256671question
Amplicon Length:   112

Gene Information

Crystallins are separated into two classes: taxon-specific or enzyme and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development these crystallins are made and then retained throughout life making them extremely stable proteins. Mammalian lens crystallins are divided into alpha beta and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs a connecting peptide and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. This gene encodes a protein initially considered to be a beta-crystallin but the encoded protein is monomeric and has greater sequence similarity to other gamma-crystallins. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes gamma-crystallins have been involved in cataract formation. [provided by RefSeq Jul 2008]

Gene Symbol:   CRYGS
Gene Name:   crystallin, gamma S
Aliases:   CRYG8
RefSeq:   NC_000003.11 NG_009829.1 NT_005612.16
Ensembl:   ENSG00000213139
Entrez:   1427
UniGene:   Hs.376209
Chromosome Mapping:   3q25-qter

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