PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CTSF, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002570; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5001255
Chromosome Location:   11:66333762-66333852question
Amplicon Length:   61

Gene Information

Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes a 50-residue flexible linker peptide and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed and it maps to chromosome 11q13 close to the gene encoding cathepsin W. [provided by RefSeq Jul 2008]

Gene Symbol:   CTSF
Gene Name:   cathepsin F
Aliases:   CATSF
RefSeq:   NC_000011.9 NG_013304.1 NT_167190.1
Ensembl:   ENSG00000174080
Entrez:   8722
UniGene:   Hs.11590
Chromosome Mapping:   11q13

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