PrimePCR™ ddPCR™ Expression EvaGreen® Assay: STAT5A, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002322; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5001059
Chromosome Location:   17:40462531-40462628question
Amplicon Length:   68

Gene Information

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by and mediates the responses of many cell ligands such as IL2 IL3 IL7 GM-CSF erythropoietin thrombopoietin and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L) which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq Jul 2008]

Gene Symbol:   STAT5A
Gene Name:   signal transducer and activator of transcription 5A
Aliases:   MGF, STAT5
RefSeq:   NC_000017.10 NG_007370.1 NT_010783.15
Ensembl:   ENSG00000126561
Entrez:   6776
UniGene:   Hs.437058
Chromosome Mapping:   17q11.2

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