PrimePCR™ ddPCR™ Expression EvaGreen® Assay: HR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0002191; Exonic

List Price:    $134.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5000954
Chromosome Location:   8:21984791-21984904question
Amplicon Length:   84

Gene Information

This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors including thyroid hormone receptor the retinoic acid receptor-related orphan receptors and the vitamin D receptors and it interacts with histone deacetylases. The translation of this protein is modulated by multiple regulatory ORFs that exist upstream of the primary ORF. Mutations in one of these upstream ORFs U2HR cause Marie Unna hereditary hypotrichosis (MUHH) an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Feb 2009]

Gene Symbol:   HR
Gene Name:   hairless homolog (mouse)
Aliases:   ALUNC, AU, FLJ98880, HSA277165, MUHH, MUHH1
RefSeq:   NC_000008.10 NG_008166.1 NT_167187.1
Ensembl:   ENSG00000168453
Entrez:   55806
UniGene:   Hs.272367
Chromosome Mapping:   8p21.2

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