PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ZBTB33, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0001790; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5000637
Chromosome Location:   X:119391917-119392144question
Amplicon Length:   198

Gene Information

This gene encodes a transcriptional regulator with bimodal DNA-binding specificity which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1) which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq May 2010]

Gene Symbol:   ZBTB33
Gene Name:   zinc finger and BTB domain containing 33
Aliases:   ZNF-kaiso, ZNF348
RefSeq:   NC_000023.10 NT_011786.16 NG_021334.1
Ensembl:   ENSG00000177485
Entrez:   10009
UniGene:   Hs.143604
Chromosome Mapping:   Xq23

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