PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SVIL, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0001667; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5000540
Chromosome Location:   10:29812771-29812909question
Amplicon Length:   109

Gene Information

This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins which cap nucleate and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Two transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   SVIL
Gene Name:   supervillin
Aliases:   DKFZp686A17191
RefSeq:   NC_000010.10 NT_008705.16
Ensembl:   ENSG00000197321
Entrez:   6840
UniGene:   Hs.499209
Chromosome Mapping:   10p11.2

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