PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MTA2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0001435; Exonic

List Price:    $130.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5000360
Chromosome Location:   11:62362839-62362944question
Amplicon Length:   76

Gene Information

This gene encodes a protein that has been identified as a component of NuRD a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains a dimerization domain and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq May 2011]

Gene Symbol:   MTA2
Gene Name:   metastasis associated 1 family, member 2
Aliases:   DKFZp686F2281, MTA1L1, PID
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000149480
Entrez:   9219
UniGene:   Hs.173043
Chromosome Mapping:   11q12-q13.1

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