PrimePCR™ ddPCR™ Expression Probe Assay: ATF4, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0051476; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191904
Chromosome Location:   22:39918055-39918179question
Amplicon Length:   95

Gene Information

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq Sep 2011]

Gene Symbol:   ATF4
Gene Name:   activating transcription factor 4 (tax-responsive enhancer element B67)
Aliases:   CREB-2, CREB2, TAXREB67, TXREB
RefSeq:   NC_000022.10 NT_011520.12
Ensembl:   ENSG00000128272
Entrez:   468
UniGene:   Hs.496487
Chromosome Mapping:   22q13.1

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