PrimePCR™ ddPCR™ Expression Probe Assay: RPL22, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0050937; exonic

 
Fluorophore:   HEX
List Price:    $201.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191866
Chromosome Location:   1:6253106-6259638question
Amplicon Length:   101

Gene Information

Ribosomes the organelles that catalyze protein synthesis consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26 and this gene actually maps to 1p36.3-p36.2. [provided by RefSeq Jul 2008]

Gene Symbol:   RPL22
Gene Name:   ribosomal protein L22
Aliases:   EAP, HBP15, HBP15/L22, L22
RefSeq:   NC_000001.10 NT_021937.19
Ensembl:   ENSG00000116251
Entrez:   6146
UniGene:   Hs.554762
Chromosome Mapping:   1p36.31

Number Description Download